The main adverse reactions were hematologic toxicity. The manifestations were: WBC, neutrophile granulocyte, blood platelet and hemoglobin all decreased, then was digestive canal symptoms. 主要的不良反应为血液学毒性,表现为白细胞下降、中性粒细胞下降、血小板下降和血红蛋白下降,其次为消化道症状。
Conclusion We can estimate morbid state by the leukocyte count and the percent of neutrophile granulocyte with acute cerebral infarction patients. 结论脑梗死急性期外周血白细胞总数、中性粒细胞百分比可作为病情轻重的评估指标。
The injury does not occur only in the Ischemia/ Reperfusion local site, but also the organ far apart by releasing oxygen free radical, activating neutrophile granulocyte, releasing inflammatory cytokine. 这种损伤并不仅仅出现在缺血再灌注的局部,还可通过氧自由基释放、中性粒细胞激活及炎性细胞因子释放等机制累及远隔重要脏器。